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In this video, the focus is on NMDA receptors (N-methyl D-aspartate receptors), a type of ionotropic glutamate receptor located at glutamatergic synapses. These receptors function as ligand-gated ion channels, playing a crucial role in regulating synaptic strength, plasticity, and memory formation. The NMDA receptor incorporates a magnesium ion in its pore, which typically blocks sodium ions from entering when glutamate binds. However, a substantial positive charge inside the membrane can repel the magnesium ion, allowing sodium ions to flow in. The video promises to explore the properties and functions of NMDA receptors in greater detail.