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Human papilloma virus, or HPV, has a strange reputation. You might know of it as a sexually transmitted infection that causes uncomfortable warts, the papilloma, but you also may have heard that it can lead to a deadly form of cancer. Both are actually true, as is the possibility that you can have HPV and experience no symptoms whatsoever. HPV isnt just one virus. There are actually over 200 strains, and the different types of HPV can result in different outcomes (which well get into a little bit later). But first, before HPV can do anything, it has to find a way into your skin. Hi, Iamp;#39;m Dr. Moscicki from the University of California Los Angeles, Department of Pediatrics. Iamp;#39;m chief of adolescent and young adult medicine, and I have been studying HPV for over 30 years now. So when youamp;#39;re looking at skin, you have several layers, and you have the very basal cell layer, that is, the layer that sits right on top of the basement membrane, and right under that is wha