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[Music] greetings everyone my name is florence dennis habeck prime vigilance head of marketing and i will be your host to share a couple of words about prime vigilance prime vigilance is an ergomet company and a leading pharmacovigilance full service provider delivering global solution for both clinical trial safety as well as post marketing pharmacovigilance and medical information we are glad you could join us today for advanced learning pharmacovigilance webinar series this webinar series aim for expert to present and provide our listener with a good understanding of the main pharmacovigilance principle and help our listeners to acquire the necessary knowledge to set up a compliant pharmacovigilance system todays webinar is titled pharmacovigilance agreement guidance before we commence id like to run through a couple of quick housekeeping matters firstly we expect this webinar presentation to run for approximately 40 to 45 minutes with a short amount of time for question and answe