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as a physician one of the most frequently asked questions that I get is about why women develop in terminal spotting or bleeding meaning bleeding between their periods when theyamp;#39;re not supposed to there are several reasons for this one of which can be hormonal which we can determine through blood work another reason could be that one might have what we call an intricate Airy lesion like a fibroid or an endometrial or uterine polyp and we would be able to determine whether someone had these in their uterus simply by doing a special ultrasound called a saline sonogram with that ultrasound we would be able to look inside the uterine cavity and see evidence of a polyp or a fibroid furthermore there might be a more worrisome reason for interventional spotting which might include a precursor to uterine cancer or even uterine cancer so potentially an endometrial biopsy might need to be done to differentiate whether oneamp;#39;s bleeding is benign or potentially more concerning it is