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In historical medical practices, many treatments may seem barbaric and cruel due to a lack of understanding of the human body. Diseases were often thought to stem from evil spirits or bad luck, leading to harmful interventions. One notable practice is trepanation, where a hole is drilled or scraped into the skull to expose the brain, believed to treat various ailments. This procedure dates back to Neolithic times, with evidence found in cave paintings and ancient burial sites. Individuals displaying abnormal behavior were often subjected to this surgery in hopes of releasing evil spirits, and it was frequently used as a treatment for seizures and epilepsy.