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hello my name is Henry Silverman and today I would like to review some concepts in informed consent in the research setting first I like to go over a few introductory remarks about an informed consent specifically I'd like to go over the legal regulatory and ethical requirements of informed consent regarding the legal history first it wasn't until 1914 that we had any legal pronouncements of the issue of informed consent in clinical medicine back in 1914 this case the swallowing dog case involved a woman who gave consent to have an examination on the ether how diagnose fibroid tumor to be examined and determined whether it was malignant or not but she expressly did not give consent to have it removed however while she was under anesthesia the physician diagnosed the fibroid tumor as being malignant and removed it anyway which on fled the justice cardozo to pronounce that every human being of adult years in sound mind has a right to determine what will be done with his body this case I...