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Health Technology Assessments (HTAs) systematically evaluate the clinical, economic, and social implications of healthcare technologies, such as drugs, medical devices, and diagnostic tests. They inform decisions regarding the adoption and use of these technologies by reviewing evidence related to safety, efficacy, and cost-effectiveness. HTAs also consider factors like patient outcomes, ethical and social implications, and the feasibility of implementation in healthcare settings. Various stakeholders, including policymakers, healthcare providers, and patients, utilize HTAs to guide their decisions. This tutorial is sponsored by Nested Knowledge, a platform that supports systematic literature reviews and meta-analyses.