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Iamp;#39;ve been asked to speak today about endocervical cells in a pap smear their significance and problems that Iamp;#39;ve encountered my practice in being sure that theyamp;#39;re there on the on a pap collection and what that means clinically why is it important that a pap smear be collected in a very specific anatomic location and in a very specific manner meaning if we get samples here why is that not as good as a sampling that occurs here in terms of screening for cervical cancer if we were to look at this region of the uterus the end of cervical canal in a microscope it has very specialized columnar cells that produce mucus we have to mention at this very specific arrow here and that is where the inside where the end of cervical cells meet the outside the squamous cells multi-layered here this very specific anatomic location has a name and thereamp;#39;s it has several names clinically itamp;#39;s referred to as the transformation zone youamp;#39;ll see this in the char