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foreign of course to deliver this lecture especially given some of the enormously influential people whoamp;#39;ve been before me I feel very honored to be here I feel honored also because this is about the interface between medicine and chemistry and frankly thatamp;#39;s what I spent most of my life trying to work at in Academia in the private sector in the pharmaceutical industry and much to my surprise it also became important when I was in government brought together people from industry Academia and government to try and Tackle this problem with a very clear objective get vaccines for the population by the end of the year and it was a very different way of working in government it was a very different way of working and one which I think could be applied to other areas as well the integration of different expertise against a very clear definable mission