Tweak evidence in 1ST

The most effcient way to tweak evidence in 1ST

DocHub is an all-in-one PDF editor that enables you to tweak evidence in 1ST, and much more. You can underline, blackout, or erase paperwork fragments, insert text and images where you want them, and collect data and signatures. And since it runs on any web browser, you won’t need to update your software to access its professional features, saving you money. With DocHub, a web browser is all you need to handle your 1ST.

How to tweak evidence in 1ST without leaving your web browser

Log in to our website and follow these instructions:

Add your file. Press New Document to upload your 1ST from your device or the cloud.
Use our tool. Locate options you need on the top toolbar to tweak evidence in 1ST.
Save your updates. Click Download/Export to save your updated file on your device or to the cloud.
Send your forms. Choose the how you want to share it: as an email attachment, a Sign Request, or a shareable link.

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Below are some common questions from our customers that may provide you with the answer you're looking for. If you can't find an answer to your question, please don't hesitate to reach out to us.

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Which cells express TWEAK?

TWEAK is also expressed in primary murine neurons28 and astrocytes28,29, in monocytes/macrophages4,21,22,30,31 and in various human tumour cell lines4,5,20,26,27.

What is the name of the tweak gene?

Tumor necrosis factor ligand superfamily member 12 also known as TNF-related weak inducer of apoptosis (TWEAK) is a protein that in humans is encoded by the TNFSF12 gene.

What is the function of TNFSF12?

The TNFSF12 gene encodes a member of the tumor necrosis factor (TNF; 191160) superfamily (TNFSF). It works with other proapoptotic TNFSF ligands to facilitate cytotoxicity in many cell types, including activated monocytes, dendritic cells, NK cells, and T cells (summary by Wang et al., 2013).

What is TWEAK protein?

The cytokine tumor necrosis factor-like weak inducer of apoptosis (TWEAK) was initially described as a member of the tumor necrosis factor (TNF) superfamily in 1997. TWEAK is a cell surface-associated type II transmembrane protein, but a smaller, biologically active form can also be shed into the extracellular milieu.

What is Fn14?

Fibroblast growth factor-inducible 14 (Fn14; TNFRSF12A) is the cell surface receptor for the tumor necrosis factor (TNF) family member TNF-like weak inducer of apoptosis (TWEAK).

What is the role of tweak?

TWEAK is a multifunctional cytokine whose effects are cell type and context-dependent. TWEAK can induce cell death, survival, growth, inflammatory and angiogenic activity, and regulate the fate of progenitor cells (Table 1, Table 2).

Is tweak a cytokine?

TWEAK is a multifunctional cytokine that controls many cellular activities including proliferation, migration, differentiation, apoptosis, angiogenesis and inflammation.

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