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foreign [Music] greetings everyone let me present you my PhD topic about prognostic factors of serum biomarkers in neurothelial cancers my vision is therapy optimization of the eurotellular cancer that is the mission I would like to assess the utilization of different biomarkers in neurotellular cancers treated with even checkpoint inhibitors these are my free ongoing projects where I will assess different biomarkers in the aspect of eurotellular cancers and Demon checkpoint Inhibitors so let me go one by one my first article titled is pre-treatment so it will pdr1 pre-treatment swivel pdr1 as a predictor of overall survival for immune checkpoint inhibitor therapy this is a published article to cancer Immunology immunotherapy so about the background I can say that even checkpoint Inhibitors revolutionized anti-cancer therapy we are talking about a really hot topic as you can see their Discovery resulted a Nobel Prize several years ago so how these drugs works here you can see a tumoro