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- The cervix is the lower narrow end of the uterus that connects to the top of the vagina. The cervix is covered by a thin layer of tissue made up of cells. Cancer of the cervix, or cervical cancer, can develop when cells become abnormal. Most cases of cervical cancer are caused by infection with a virus called HPV, or human papillomavirus. The HPV virus can cause cells to become abnormal over time. One way to prevent HPV infection is by getting the HPV vaccine. You can also prevent cervical cancer by having regular screening tests and follow-up treatments if needed. Cervical cancer screening may include Pap tests, HPV tests, or both. Pap tests check for abnormal cells in your cervix. HPV tests check for the HPV virus. In both tests, cells are taken from the cervix in the same way and sent to a lab for testing. Cervical cancer screening is recommended starting at age 21. How often youamp;#39;re screened and which tests you have depends on your age and health history. It takes many yea