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since widespread screening programs for cervical cancer were developed the incidence and mortality from that cancer have decreased by almost fifty percent there are about 11,000 new cases of cervical cancer diagnosed annually in the United States with about 4,000 deaths up to half of all the women who are diagnosed annually with cervical cancer have never been screened and another ten percent have not been screened for five years cervical cancer is directly related to HPV infection infection with a high-risk HPV subtype is a risk factor for developing an abnormal pap smear and ultimately cervical cancer HPV infection is very common especially in young women in adolescence however women under 30 with intact immune systems are able to clear the virus in most cases so although HPV infection is necessary for cervical cancer to develop the vast majority of women with HPV infection will not develop abnormal pap smears or cervical malignancy the American committee of OB gyns developed a new e