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the FDA recognizes the thin prep Pap test as docHubly more effective than the conventional pap smear for the detection of low-grade squamous intra epithelial and more severe lesions in a variety of patient populations but the clinician also plays the key role in making these results possible optimal sample collection and adequate fixation are the most important factors in improving the reliability of cytology and reducing sampling errors steps taken by the clinician from patient education to improved sampling technique may help ensure that the sample collected maximizes the potential of the Pap test when a Pap test is compromised it may lead to an unsatisfactory result a variety of factors can contribute to unsatisfactory specimens these factors include patient biology use of personal lubricants prior to exam excessive use of lubricant on the speculum and improper collection technique focusing on factors you can control will help reduce unsatisfactory pap results and subse