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- A couple of weeks ago I played a game of noughts and crosses, tic-tac-toe, and my opponent was DNA and the DNA won. How is that possible? How can you play a game against DNA? There are these nine wells. They represent the game grid and in each of those wells is a special solution of DNA. And in addition to that, over to one side there are all these other solutions of DNA that I can choose from. They represent the moves that I can make. The way we set it up is DNA takes the first move and plays the center square. When itamp;#39;s my move, suppose I want to play this square, letamp;#39;s call that square number four. So I find the solution that represents playing square number four on my first move and I pipette that solution, just the right amount, into each one of those nine wells. Thatamp;#39;s how I tell the DNA in those nine wells which move I want to make. We then put those nine wells into a special machine. Eventually one of those wells starts to glow, specifically, it starts