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Health Technology Assessments (HTAs) systematically evaluate the clinical, economic, and social implications of healthcare technologies, aiding in decision-making regarding their adoption and use. This includes drugs, medical devices, and diagnostic tests. HTAs examine evidence related to safety, efficacy, and cost-effectiveness, while also considering patient outcomes, ethical concerns, social implications, and the feasibility of implementation in healthcare settings. Various stakeholders, including policymakers, healthcare providers, and patients, utilize HTAs to inform their decisions. The tutorial is sponsored by Nested Knowledge, a platform dedicated to supporting systematic literature reviews and meta-analyses.