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The history of present illness is crucial in history taking and consists of three main components known as the "three Cs." First, determine the system involved, such as cardiac, respiratory, gastrointestinal, central nervous system, renal, endocrine, or hematological. This identifies "what is the case." Second, establish the cause of the symptoms, identifying the disease affecting the involved system. Lastly, assess any complications arising from the disease. For example, if a patient presents with breathlessness, these three components help in diagnosing and understanding the patient's condition effectively.