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dr. Bobby Mazzara for the medical news minute now heres a little clinical pearl with recent data to support it did you know there is data to support an association between diagonal earlobe creases and heart disease the so called franc sign present and such notable individuals is Steven Spielberg and George W Bush ing to photos from some of the worlds best paparazzi now a study from China published in the British Medical Journal online found a positive correlation between diagonal earlobe creases and coronary artery disease using 558 consecutive patients that underwent coronary angiography the results of the study showed using multiple regression analysis that diagonal earlobe creases were independently associated with docHub coronary artery disease this was defined as a greater than 50% obstruction in at least one major coronary artery the take-home message for those docs that still use an otoscope on the way towards the eustachian tube have a look at the year lobe for a diagona