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Does Marijuana Cause Strokes and Heart Attacks? Does the so-called dark side of cannabis include stroke, here said to be associated with non-synthetic marijuana, by which I assume they mean, uh, marijuana. There have been case reports of artery damage due to the vasoconstrictor effect of cannabis, something thats been well documented. One study found cannabis users had 100 times greater odds of suffering from something called multifocal intracranial stenosis, where the arteries inside your brain clamp down at multiple points, but thats a rare condition. What about strokes? The lack of high-level evidence regarding the adverse effects of marijuana usage on brain artery health has led to this notion that recreational marijuana may not be a problem, so they decided to put it to the test. You want high level evidence? they said. Well, how about a study of literally millions of pot smokers? OK, then. And they found that recreational marijuana use did seem to be associated with an incr