Snip pecularity in AFP

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Aug 6th, 2022
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How to snip pecularity in AFP

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the Philippines and Germany commit to a broader defense cooperation Arrangement Sunday August 4 Philippine and German defense ministers gibbo choro and Boris Pistorius commit to establishing long-term relations between their Armed Forces to expanding training and bilateral exchanges explore opportunities to expand bilateral armaments cooperation and engage in joint projects meantime the Philippines and Vietnam will hold its first joint exercise on Monday August 9 and a move to boost Maritime cooperation both Nations have competing claims over some parts of the South China Sea both have filed separate claims with the United Nations for an extended continental shelf to recognize their entitlements beyond their 200 nautical mile exclusive economic zone Manila has been deepening military ties with various Nations as tensions flare between China and the Philippines which have traded accusations over runnins in disputed areas of the South China Sea

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An AFP tumor marker test is a blood test that measures the level of AFP (alpha-fetoprotein) in a sample of your blood. Its usually used to help diagnose certain types of cancer and to check how well treatment is working. AFP is a protein that the liver makes when its cells are growing and dividing to make new cells.
In HCV patients with cirrhosis, an AFP level 6 ng/ml was observed to be associated with the development of HCC in the multivariate analysis. AFP is used as a serological marker of HCC and employed in combination with USG for HCC screening (17,18).
A screening alpha-fetoprotein (AFP) cutoff level of 2.0 multiples of median (MoM), followed by acetylcholinesterase (AChE) confirmatory testing on positive results, is capable of detecting 96% of open spina bifida cases with a false-positive rate of only 0.06% in non-blood-stained specimens.
AFP can be elevated in patients with CHC or cirrhosis without any evidence of HCC[81]. A persistent AFP value of 17.8 ng/mL was noted to have a 98.6% specificity, 35% sensitivity and a positive predictive value of 97.7% in identifying patients with cirrhosis[82].
AFP tests are good tools for detecting genetic disorders or neural tube defects. Up to 9 in 10 fetuses with neural tube defects were diagnosed because the AFP test detected abnormalities. But AFP tests arent perfect. In every 1,000 pregnant people who get the AFP test, up to 50 get abnormal results.
Alpha fetoprotein (AFP) is a protein produced by the liver and yolk sac of a fetus. AFP has no normal function in adults. The alpha fetoprotein test (AFP) is a blood test performed to measure, diagnose, or monitor fetal distress or fetal abnormalities. It can also detect some liver disorders and some cancers in adults.
Using 20 ng/ml as a cutoff, AFP showed a 63% sensitivity and 88.7% specificity. Combined use of US and AFP showed 97% sensitivity and 82.3% specificity. ROC curve results for AFP levels demonstrated that using 5.6 ng/ml as a cutoff, AFP will have a 77% sensitivity and 78% specificity for HCC detection.
Notably, both AFP cutoff levels of 20 and 400 ng/mL are used frequently in daily practice; 20 ng/mL is the upper limit of normal AFP level and 400 ng/mL is the cutoff value used in both the CLIP and TIS staging systems [10,11].

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