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hi this is mary from open helix with this weeks tip of the week now if youre seeing this tip someplace else be sure to come back by our blog at blog.openhelix.com for additional details links to the site links to the literature that im talking about today and so on today were going to be talking about a tool called a snip effect 4.0 now snip effect has been around for a while but i saw a paper recently that described some of their new features and wanted to check it out so if you want to go to their site see snip effect.switchlab.org then youll find yourself on the homepage it looks like this now lets talk about whats in snip effect 4.0 so its really about human mutation very and variations that would affect human proteins and they explore this in a number of different ways im going to go to the about page to tell you about one of the key features about the data that youll youll explore here now it does not contain every snip and db snip theres a subset of variations that t