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an entire set of 23 human chromosomes is called a genome the human genome is composed of 3 billion base pairs variation at a single base pair is called a snip or single nucleotide polymorphism when the body makes new cells it doesnt make many mistakes but nobodys perfect sometimes when the genome is copied to make a new cell a single base pair gets left out added or substituted single base pair substitutions create slips there are around 10 million snips in the human genome which account for many of the genetic differences between you and everyone else on the planet some snips account for differences in appearance others can affect how we develop diseases or respond to drugs most snips however seem to lead to no observable differences between people at all since variants are passed on from one generation to the next the number of differences between your DNA and your neighbors can tell you how closely you are related to each other