Snip identification in AWW smoothly

Aug 6th, 2022
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How to Snip identification in AWW

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hi my name is fenjal and im a biology undergrad at the maharaja university of baroda in india and what im going to present today is work that i did with my colleague devin at dr coach painter singhs lab at the same university in the summer of 2019 and what weve done is weve made a program that can tell the user what strain of the leprosy bacillus theyre dealing with based on just a few inputs of snips so ill begin by explaining what snips are snips are single nucleotide polymorphisms which are differences of one nucleotide in what are otherwise similar genetic sequences snaps can be very informative they can be used for genotyping of a pathogen into lineages which can give us insights into their phylogeny and phylogeography drug resistance mutations are also often a result of snips mycobacterium library and mycobacterium tuberculosis are examples of pathogens where snips can give us such info mycobacterium electric or the leprosy bacillus is the causative agent of leprosy and it

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Single nucleotide polymorphisms, or SNPs (pronounced snips), are DNA sequence variations that occur when a single nucleotide (A,T,C,or G) in the genome sequence is altered. For example a SNP might change the DNA sequence AAGGCTAA to ATGGCTAA.
Whole genome sequencing has been widely used in SNP identification and analysis. Typically, hundreds of thousands of SNPs are identified through genome-wide comparison between a targeted genotype and the reference genome. These SNPs might be useful in developing large-scale, genotyping-based breeding selection tools.
An example of an SNP is the substitution of a C for a G in the nucleotide sequence AACGAT, thereby producing the sequence AACCAT. The DNA of humans may contain many SNPs, since these variations occur at a rate of one in every 100300 nucleotides in the human genome.
The SNPs in the coding region of gene are divided into two types: synonymous and nonsynonymous SNPs. The synonymous SNPs do not change the amino acid sequence of protein or not affect the protein function. The nonsynonymous SNPs are divided into two types: missense and nonsense.
Single nucleotide polymorphisms or SNPs (pronounced snips) are a common type of genetic variation found among people and are responsible for the diversity among individuals, including whether or not you have curly hair, the inter-individual differences in drug response, as well as complex and common diseases.
During the past years, various SNP panels have been published for individual identification [2025, 4147]. The SNPforID consortium developed 52 SNPs for individual identification [35].
SNP is a change in the single-nucleotide of a genome. Also, it is a type of mutation. Mutation is the variation in DNA base pairs caused due to insertion, deletion, duplication or substitution of base pairs.
How To Analyze Your Single Nucleotide Polymorphism (SNP) Chip Data Cluster your SNPs. First, sort the data by chromosome, and then by chromosome position, in order to cluster your SNPs. Choose which SNPs to pursue. Find your SNPS on the chromosome. Identify gene functions. Dig deeper.

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