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hello and welcome to this talk its Friday the 27th of January now I want to give you some information from an official UK government uh publication published yesterday and Im going to give you one piece of information from the Autumn covid-19 vaccine booster program the Autumn booster program it turns out that theres this idea called the number needed to vaccinate so its a bit like the number needed to treat and it turns out that you need to to vaccinate 43 600 people between the ages of 50 to 59 to prevent one hospitalization so 43 600 vaccinations in the 50 to 59 year old age group to prevent one hospitalization and to prevent one serious hospitalization in the 50 to 59 age group to prevent one serious hospitalization someone needing oxygen or ventilation you need to vaccinate over a quarter of a million people 256 400. and uh we actually vacc we actually oxygenate fairly readily in hospitals because our Target saturations are 94 to 98 percent and that means we give oxygen to qu