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Motor Neurone Disease (MND) affects approximately 5,000 people in the UK at any given time. It involves motor neurons in the brain and spinal cord that transmit messages to muscles, leading to loss of movement, weakness, and wasting. MND encompasses various conditions that impact these nerve cells. Early symptoms may include mild weakness, clumsiness, tripping, or slurred speech, but experiences vary among individuals, complicating diagnosis. There are no definitive tests; diagnosis usually involves excluding other conditions and monitoring symptom progression. MND is life-shortening, with no cure available, but specialist support for symptom management and social care assessments can enhance quality of life and independence.