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The key point of the text is that many people apply for postdocs incorrectly, by simply sending out a generic CV and expressing a desire to work in a lab without any specific connection to the researcher's work. The speaker encourages aspiring postdocs to stand out by taking the time to truly engage with the researcher's work before applying, demonstrating a genuine interest in their research. This personalized approach is emphasized as a way to increase the chances of success in the application process.