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In America, the blood industry is a multibillion-dollar market, valued at $3.3 billion in 2021, making up over 2% of U.S. exports. However, demand often surpasses supply, leading to sporadic shortages that can be life-threatening. The blood supply currently sits at just a one-day reserve. Notably, a historic FDA study may change the ban preventing gay men from donating blood, as the existing ban is criticized for not being scientifically justified. Major companies like Grifols, CSL Plasma, Takeda's BioLife, and Octapharma dominate blood and plasma collection. Donors are compensated for their contributions, which are used in therapies by large pharmaceutical firms.