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Dr. Rishi Desai from Osmosis shares three essential tips for taking a thorough patient history. While the mechanics involve understanding the chief complaint, history of present illness (HPI), past medical history, medications, allergies, family history, social history, and review of systems, effective execution goes beyond just collecting data. His first tip emphasizes the importance of listening well and showing empathy towards the patient. He notes that patients seek human interaction rather than robotic responses, underlining the necessity of building rapport and understanding their concerns to gather meaningful information.