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[Music] hello and welcome to this enquiry demonstration in this demonstration we will show how to do a sample size calculation for the two-sample t-test using enquiry enquiry is a widely used and fully validated trial design platform with access to hundreds of individual power and sample size routines for a variety of different tests and designs ranging from simple t-tests up to complex adaptive designs such as sample size reestimation the two-sample t-test is one of the most widely used statistical tests due to its robustness to both small sample sizes and to deviations from normality to do a sample size calculation for the two sample t-tests in inquiry we will first cover briefly how to do sample size calculations in inquiry generally in enquiry sample size calculations will occur in the spreadsheet in the top left-hand corner of enquiry when you open a new table in inquiry this spreadsheet consists of rows and columns where each row is a required input for the sample size or power