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To assess an unwell patient, use the mnemonic "SAMPLE." The patient's age influences how you communicate; with adults, talk directly, while with children, consider their parents' input and adjust your language to prevent fear. "SAMPLE" components include: S (Signs and Symptoms), A (Allergies), M (Medications), P (Pre-existing medical conditions), L (Last meal), and E (Events leading to the condition). This assessment helps determine the appropriate action and provides crucial information for EMS or family members. Remember, signs are observable, whereas symptoms are reported by the patient.