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Prescription drug prices in the U.S. have steadily increased over the last decade, with a 2021 Gallup poll indicating that about 18 million U.S. adults struggle to afford necessary medications. In response, pharmacist Nate operates two pharmacies in Ohio: Pickerington Pharmacy, a traditional pharmacy accepting insurance, and Freedom Pharmacy, a self-pay alternative where customers can save significantly on common generic medications by paying out of pocket. Approximately 85% of medications in the U.S. are generics, which are generally affordable. Pricing often varies due to negotiations between pharmacy benefit managers, impacting costs at the register and pharmacist reimbursements.