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In this video tutorial, Carla discusses essential questions for gathering past medical, drug, and social history during a subjective examination. She introduces the acronym "hashtag thread Sox" to represent key medical history components. The breakdown is as follows: the hash symbol indicates fractures; T for thyroid conditions; H for heart conditions; R for rheumatoid conditions; I for epilepsy; A for asthma and breathing pathologies; D for diabetes; S for previous steroid use; O for osteoporosis; C for personal or family history of cancer; and S for surgical history. Carla reiterates the acronym's significance for thorough assessments.