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in the event of a shortage of hand-rubbed formulations health professionals can manufacture them themselves by following World Health Organization guidelines a 10 liter batch requires 96% ethanol 3% hydrogen peroxide known as oxygenated water 98% glycerol commonly known as glycerin used such a humectant in a large glass or plastic bottle with a lid or screw cap to allow mixing hovering the alcohol add the hydrogen peroxide then the glycerin finally add distilled or boiled and cold water to obtain 10 liters of solution close the recipient quickly to avoid evaporation mix the preparation by gently shaking the contacts then pour the substance into hermetic dispensers wait 72 hours before using the substance the time required for bacterial spores potentially present in the alcohol or in the dispensers to be destroyed by the hydrogen peroxide