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a heart attack occurs when the flow of blood to the heart is severely reduced or blocked like all other tissues in our body heart muscles also need oxygen rich blood to function properly now the arteries wrapping around the heart are called coronary arteries which Supply the oxygen rich blood to the heart coronary artery disease is the main cause of heart attack the blockage of arteries is usually due to the buildup of fat cholesterol and other substances the fatty cholesterol containing deposits are called plucks and the process of plug buildup is called atherosclerosis sometimes a plug can rupture and form a clot that blocks the blood flow a lack of blood flow typically caused by blockage of a coronary artery can damage or destroy a part of the heart muscle when a part of your heart canamp;#39;t pump because of its dying from lack of blood flow it can disrupt the pumping sequence of your entire heart that reduces or even stops blood flow to the rest of your body which can be deadly