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BMI (Body Mass Index) is a measure of body fat based on height and weight, and a high BMI can increase the risk of certain diseases. It is calculated by dividing weight in kilograms by height in meters squared. For example, to convert 175 pounds to kilograms, multiply by 0.4536, resulting in 79.38 kg. To convert height, first change feet to inches (5 ft 9 in equals 69 inches), then convert to meters by multiplying by 0.0254, resulting in 1.75 m. Using the formula, the BMI for this example is 25.8. The video also provides a formula for calculating BMI using U.S. metrics (pounds and inches) and includes a chart listing weight categories.