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hello and welcome welcome to this session so in this session i am going to talk about the dissolution how dissolution apparatus can be used very differently for modifying or changing the constituent or the ph of dissolution medium while dissolution run is under progress yes you can do that by using a simple dissolution apparatus like apparatus 1 or apparatus 2 you need not to have the apparatus 3 or apparatus 4 to experience the change into the dissolution medium or ph to your drug product so i am going to explain you a very simple trick right which will definitely blow your mind so if you want to understand that and if you are really curious now how this can be done watch out this video so uh in case of the resolution apparatus one or two it may be let us say ir product or the modified release type product and if you are performing the multi-point dissolution you need to withdraw let us say 10 ml of the sample after every 10 minutes and you may have to again replenish the same amount...