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you might otherwise benefit from going to a more infrequent dosing schedule to drive down the shpg a bit because you still have low free t and free dhc symptoms whatamp;#39;s up guys derek from placements.com today weamp;#39;re going to be talking about what you should do before using an ai before you hop on the ai train and start inhibiting aromatase as well as shbg and how to manipulate it too so a lot of people um they think shbg is the devil they also think that estrogen is the devil you need to inhibit it i feel like the estrogen the conversation is becoming a bit more uh you know well known in the community about how you shouldnamp;#39;t just indiscriminately inhibit aromatase proactively um and even if a number on a piece of paper is you know double the reference range if your testosterone is like [] 2 000 nanograms per deciliter expecting your your estradiol to be 30 is kind of ridiculous when you think about it so one of the first things with ais is like iamp;#39;m gon