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Donating Peripheral Blood Stem Cells Congratulations! You are the best match for a patient in need of transplant. While there are two ways to donate, your patient will be best served by a peripheral blood stem cell donation. Bone marrow is the soft center of your bones. When the marrow cells leave your bones and circulate in your blood, they are now called peripheral blood stem cells or PBSCs. These wonderful cells make your blood cells, including white blood cells that form your immune system. Your immune system fights infection and illness. Your patient is sick and needs a new immune system. Your patient will prepare for donation by destroying his or her own bone marrow, like cleaning spoiled food out of a refrigerator. Your transplanted cells will grow a new immune system inside the patients body, like refilling the refrigerator with fresh groceries. It is very important that you understand the risks of donation, communicate your concerns and difficulties, and commit fully or quit
