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In this video tutorial, Carla from Clinical Physio discusses the importance of asking key questions about past medical history, drug history, and social history during a subjective examination. She introduces the acronym "hashtag thread Sox" to help remember the important points to ask. Each letter in the acronym represents different medical conditions and factors to consider, such as fractures, thyroid conditions, heart conditions, rheumatoid conditions, epilepsy, asthma, diabetes, previous use of steroids, osteoporosis, personal or family history of cancer, and history of surgery. Remembering and asking about these key points can help in providing comprehensive care to patients.