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in this lesson we were talking about the side effects of statin medication use so were going to talk about what statins are and some of the mild and severe side effects of use of statins what are statins statins are medications used to lower or reduce blood cholesterol levels so they all have the suffix statin in their name one example is another one is simvastatin and another one is rosuvastatin now the statin medications inhibit synthesis of cholesterol via inhibition of hmg-coa reductase enzyme so they inhibit the activity of hmg-coa reductase enzyme which is involved in producing cholesterol so there are many many different enzymatic steps in between hmg coa reductase and cholesterol but this is the rate limiting step in cholesterol synthesis so if statins bind to this enzyme they prevent cholesterol production or synthesis but the problem is statins may cause a variety of mild and or severe side effects were going to talk about those s
