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[Music] [Music] starting that drug early in in these patients who are hospitalized not only is safe lowered their blood pressure a little bit but not too often to have them need to stop didnt hurt their kidneys and then when we followed them for the next eight weeks we saw that compared to older therapies this news to keep a trail starts and started in the hospital actually made patients better they were less likely to get sick again and get so I think its exciting it for somebody like me whos a heart failure doctor it simplifies things so I dont have to start on old therapy in the hospital get the patients back in clinic and then try and switch them over to this newer therapy I can just start from the beginning with the therapy that I think is going to be most effective [Music]