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The speaker's career began in the early 1980s, focusing on mitral and aortic valve surgeries, with 80% of clinical activity dedicated to valve operations. Aortic valve surgery is primarily indicated for aortic stenosis, where the valve does not open properly, necessitating replacement as no medical therapy exists. In contrast, mitral valve surgery is mainly for mitral regurgitation, characterized by a leaking valve. Aortic valves are replaced when stenotic (narrow), while mitral valve prolapse with regurgitation can often be successfully repaired, achieving over 90% success in repairs.