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Music intro Iamp;#39;ve been at Temple University since 1973 so Iamp;#39;ve been here for 42 years and have enjoyed pretty much every minute of my time here. My dad had a myocardial infarction when he was in his early forties, lived for about 10 years after that with congestive heart failure and then died of sudden cardiac death. After my father died, I changed my research focus to really cardiac electrophysiology and mechanisms of vascular disease. Iamp;#39;m happy I did that. An infarction is when a blood vessel thatamp;#39;s been diseased, it has disease, atherosclerosis, develops a blood clot which blocks the blood flow through that artery. Then the cells that are downstream of that blocked area die. You canamp;#39;t regenerate cardiac myocytes very well so once you kill some, itamp;#39;s very difficult to replace them. My group was at the forefront of figuring out the fundamental aspects of cardiac contraction, what makes cardiac myocytes contract. Our lab showed an ion, the