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Here are the top 20 Frequently asked Interview Questions about VALIDATION in Pharmaceutical industry. SUBSCRIBE TO CHANNEL FOR MORE INFORMATIVE CONTENT. We will start this series of questions very basic one, What is validation? answer is In simple words it is confidence building procedure for applied process that it will give expected results. USFDA defines it as, The collection and evaluation of data, from the process design stage throughout production, which establishes scientific evidence that a process is capable of consistently delivering quality product. Second question When we should perform validation ? Here are the four cases given when we can perform validation. First one is Before introduction of a new method in use. Second case is Whenever there is change in the conditions for method has been validated e.g. Instrument or equipment with different characteristics. Third case is Whenever the method or process is changed. And forth case is Whenever there is change other th