Replace EU Currency Field into the Clinical Trial Agreement and eSign it in minutes

Aug 6th, 2022
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How to Replace EU Currency Field into the Clinical Trial Agreement

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this video outlines in short how to make changes to an application dossier in the context of a response to a request for information or rfi how to save and view the changes on the application and how to view the other drafts of the application in the evaluation section of the trial page you can see two rfis related to the validation of the trial use the arrows to expand the working area of the first rfi and click on the lock button to be able to work on this rfi and respond to it if for the rfi response you need to change the application based on the contextual information provided in the rfi click on the change application button and then on the confirm button a green message appears on the upper right corner informing you that a new version of the application is being drafted on top below the trial title the blue colored ribbon informs you that a new version has been drafted you can have an application version open in draft mode to address one rfi at a time received in each section s

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The Regulation also makes it more efficient for EU Member States to evaluate and authorise such applications together, via the Clinical Trials Information System. The purpose is to foster innovation and research in the EU, facilitating the conduct of larger clinical trials in multiple EU Member States/EEA countries.
EU-CTD obliges multiple safety submissions to NCAs and ECs, whereas EU-CTR requires all safety reporting via EudraVigilance. A single safety report can be submitted for trials involving more than one IMP, but all unexpected events which affect a trials benefit-risk balance must be reported within 15 days.
Content. The application content and assessment are divided into two parts: Part I contains scientific and medicinal product documentation; Part II contains the national and patient-level documentation (see Table A).
Starting on 31 January 2023, CTIS will replace the EudraCT portal and clinical trial sponsors will be required to use the portal to apply for authorization to run a clinical trial.
Unlike the Directive, the Regulation will be binding in its entirety and will be directly applicable in all EU/EEA Member States: the 27 EU countries and Iceland, Liechtenstein and Norway not including, of course, the UK following the Brexit.
The legal representative ensures compliance with the Sponsors obligations under EU CTR and notifies the sponsor immediately in the case of becoming aware of incompliance with EU CTR.
On 31 January 2022, the Clinical Trials Regulation (CTR) will come into application harmonising the submission, assessment and supervision processes for clinical trials in the European Union (EU). The backbone of the changes brought about by the CTR is the new Clinical Trials Information System (CTIS).
EU-CTR leverages a new portal and database called the Clinical Trial Information System (CTIS) and enables a centralised, single electronic submission instead of multiple submissions with different dossiers.

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