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In this video tutorial, Eugene Lachlan explains how to replace missing values using the mean imputation method in R. He emphasizes the importance of addressing missing values in datasets to perform basic data analyses, such as calculating means. The tutorial will utilize a fictitious dataset found in CSV file number 77, which is accessible through a link in the video description. Eugene begins by demonstrating how to load the dataset into R using the read.csv function and prints the results, setting the stage for further analysis and imputation techniques. This video is part of a series focused on data manipulation in R.