Replace Cross Out Option in the Clinical Trial Agreement and eSign it in minutes

Aug 6th, 2022
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How to Replace Cross Out Option in the Clinical Trial Agreement

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um Im excited today to kick off the fall clinical trials toolkit series um our first one is the office of sponsored programs clinical trial agreement review and negotiation um today we have Rachel humberson she is the interim assistant director um from research office and office of sponsored programs and we also have um Julie even though I practiced it Julie Im going to mess it up Anna okay is that right yeah okay she is a negotiator with research with the research office and office of sponsored programs um before I read their um their bios and a fun fact about them again we are offering continuing education to WVU employees so if um you would like CES please indicate that and please put your name um an email address in the chat so for attendance purposes um Im trying to think if theres anything else oh if you have a question during this um feel free to put it in the chat well be watching it and um I will stop Rachel and Julie and let them know what your question is and then also

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A CTA serves as a legally binding contract between a sponsor, site, and researcher, and outlines each partys responsibilities and obligations for the clinical trial.
Clinical Trial Research Agreements The CTRA will outline the obligations and responsibilities of both the sponsoring institution and the participating site with regards to: Protocol, conditions of ethics approval, applicable standard operating procedures, regulatory and legislative requirements. Conduct of the study.
A CTA should describe and acknowledge responsibilities, terms of collaboration, requirements for payment and reimbursement, publication and intellectual property terms, indemnification and or insurance, subject injury coverage, guidelines for dispute resolution, grounds for termination of contract and possibility of
If a subject does not take at least 17 doses in the first cycle, the subject will be replaced because he/she has not taken enough drug to confirm safety at that dose level.
Informed consent must be obtained. The consent language agreed to, and the process for obtaining consent, must be carefully documented. Research subject privacy and confidentiality must be adequately protected. The ongoing safety of research subjects must be adequately monitored.
Any change or correction to a CRF should be dated, initialed, and explained (if necessary) and should not obscure the original entry (i.e., an audit trial should be maintained); this applies to both written and electronic changes or corrections (see section 5.18.
Clinical Trial Agreement (CTA) Description of the Project. Sponsor, CRO (Contract Research Organization) and Site Responsibilities. Publication and Intellectual Property Terms. Indemnification and Insurance. Recording Keeping and Inspection. Guidelines for Dispute Resolution. Grounds for Contract Termination.
The study close-out visit occurs once participants are no longer receiving investigational treatment, all the data have been collected (there are no more outstanding adverse events all outstanding queries/data clarification forms have been resolved appropriately), the database is locked and ready for statistical

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