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In this video tutorial, the presenter demonstrates how to remove all instances of a specific element from a list using a for loop. The initial approach involves iterating through the list (backpack) and checking if an item equals "pizza slice." If it does, the item is removed with the command `backpack.remove(item)`. However, the presenter highlights a critical issue: removing items from a list while iterating through it can disrupt indexing, leading to unexpected results. This practice is discouraged in Python and other programming languages with similar constructs, as it can create logical errors in the loop's execution.