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To safely remove a tick, avoid harming it, as this can cause it to salivate and potentially introduce pathogens from its saliva into your body. Using tweezers, grasp the tick as close to the skin as possible and pull straight up slowly and steadily without twisting or jerking. Concerns about the tick's mouthparts remaining in the skin are minimal, as ticks have small mouthparts, not a significant head. The key is to remove the tick carefully to minimize the risk of infection.