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in this video ill elaborate on an indexing strategy for improving random chunk access efficiency for ohmy tiff and how to generate an indexed ohmy tip of your own for use in avivator our viv based image viewer for a bit of background viv loads atomic chunks directly from oh me tiff and ome ngff via http requests this contrasts most existing web clients which rely on server rendered image tiles therefore the underlying binary layout for each format tiff for oh me tiff and tsar for omi and gff govern how efficiently individual chunks may be randomly accessed these differences are nicely depicted in this figure from josh moore on twitter displaying how zar was designed for the cloud and allows direct chunk access whereas tiff a monolithic file requires seeking to find chunks from different 2d planes motivated by approaches that achieve efficient random access for monolithic formats in genomics we propose indexing ome tiff to improve read efficiency our proposed format is the original oh